Take a look at this thread over at SCS:

Bloggers Beware

Make sure to monitor your comments so that a spammer can’t post on your blog.

How do you do that?

In Blogger:
1. Go to Settings
2. Go to Comments
3. Go to Enable Comment Moderation
4. Enter your email address
5. Save Settings

This will give you an email message whenever someone leaves a comment. You will need to approve it before it will appear on your blog.

0r:
1. Go to Settings
2. Go to Comments
3. Go to  Show Word Verification for  Comments
4. Save Settings

This will give readers a row of letters to type. After they type the letters correctly, their post will be live on your blog.

In Typepad:
1. Go to Configure
2. Go to Feedback
3. Find Moderation and click on Hold Comments for Approval
4. Save Changes

This will give you an email message whenever someone leaves a comment.
You will need to approve it before it will appear on your blog.

or

1. Go to Configure
2. Go to Feedback
3. Find Typekey Authentication and click on Optional
4. Find Unauthenticated Commenters
5. Click on Always require email address and  Always Require Captcha
6. Save Changes

This will give readers a row of letters to type. After they type the letters correctly, their post will be live on your blog.

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